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Risk of Adenocarcinoma in Barretts Esophagus; Long-Term Effect of Doxazosin, Finasteride, and Combination for BPH; Once Daily Valacyclovir to Reduce Herpes Transmission; Use of B-Type Natriuretic Peptide in the Evaluation and Management of Acute Dyspnea; Association Between C-reactive Protein and Age-related Macular Degeneration; VZV Reactivation in Astronauts
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The National Institutes of Health (NIH) wants all research supported with NIH funds to be shared with other investigators and made available to the public, but how can this philosophy be reconciled with privacy laws and concerns?
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In emergency medicine and critical care, clinical trials are difficult to conduct. The unpredictable and time-sensitive nature of these specialties means that controlled, randomized, clinical trials are difficult, sometimes impossible to design.
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Smallpox vaccine draft guidance issued by FDA; New technology, lack of consent leads to lawsuit
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A cardiovascular surgeon develops an experimental intravascular blood oxygenation device that has the potential to eliminate the need for mechanical ventilation in severely injured patients. However, testing the device in human patients would be unethical because of the great risk of harm, and the still-unknown chance for benefit.
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The following summary of selected abstracts from 3 meetings will be published in multiple parts. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003. The Infectious Disease Society of America (IDSA) met in San Diego October 9-12, 2003. The American Society of Tropical Medicine and Hygiene met in Philadelphia December 3-7, 2003.
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The 50-year-old drug colistin was used successfully in 14 of 23 cases of serious infections caused by multiply resistant Pseudomonas aeruginosa .
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Antibiotic administration for only 8 days to patients with ventilator-associated pneumonia was not inferior to 15 days of therapy.
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A randomized, double-blind, placebo-controlled trial of short-course dexamethasone therapy as an adjunct to antimicrobial therapy was conducted among children 3 months to 11 years of age with hematogenous suppurative arthritis in Costa Rica from 1998 to 2000.
